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SELECT 
  1 
FROM 
  cscart_multi_declock_keys 
WHERE 
  key_id = '41df5b3ef6be2e48a7c56da9b919bfb54f32660438a513e76d58a2ca9808f233' 
  AND token = 'HMxKYb9wQVTQ6bSNLG7esHRkmqd4NfVw0Xb5VGjITrI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}