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SELECT 
  1 
FROM 
  cscart_multi_declock_keys 
WHERE 
  key_id = 'd2246f0414d761091f74df68cf9697616355d466e6d43c06d93147c99b7483e2' 
  AND token = 'qzMCSJ948GB88iIzhB2u04xch2nRf+pSFuWe70Quhg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}