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SELECT 
  1 
FROM 
  cscart_multi_declock_keys 
WHERE 
  key_id = 'f7e5af4ccaf52a30f0bea1b3348a278000f603dc76b0fe268016a53583b21082' 
  AND token = 'IocyAkCcui3oXRKv5NnmDw62EecrdQLHHHIMyj/VF7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}