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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '1961f460684e88eda6a66964d6a1ad72228f97d880a736a21e1354cee10df732' 
  AND token = 'XqUwFfluLNlk8KsrKJFQ7mC0oQ3+mmwwpV0pBuWs8sA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}