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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '4650aa1c0fd0cfca060bbd96dda83498bc6a5d4e482d3c38ddf4a914429dec6f' 
  AND token = 'EmpCqNaDw9NViG7y5dJ8v4CY+RNHVLdAGe+FeGoLW+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}