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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'e969c392da004782596cea383c071c2e48eabca51fcbd24a095ddd30727ffc78' 
  AND token = 'uAA4x6C0lsdChcO6gj4z6zwvpuFo2z26CYd3VH7JoD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}