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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'f8dedb31d39e60d800c6ab234d04d8759275e8df1fa6ab27e0276288fb2a9b1a' 
  AND token = 'WS1irF8S7wM3MwjMCz23rzdzkVg5/WUzHmyAdPzmcFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}