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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '8002ce624deeac437a33cb35eddf9a44c6205b6f3e5b4503f54e72826116ec19' 
  AND token = 'wSRDMo+lEolakQgiRRMkVOZ22PBVXWVl5JdWehfAXEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}