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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '54168c34df2ab3d5a0b247112285241ae19cc6290c92c35f1a1b04c7e6b87bfe' 
  AND token = 'TooGcxAVM7PZxbB2GoK37ryMDZuk1Xgj5ZFOTtRTzcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}