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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '4f3baaefa3fc6dc122f0415d366a7ee612340ae81bdc1bc8ce2b8f9be2deb7fd' 
  AND token = 'PEb499wtcNtEwoYLolAoIJKsMiOd82vAlc51nT3DdDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}