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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '541d745e20e90735b4f8b00360b00da07e5ea8526a8922a5345e33cb1285fd56' 
  AND token = 'OI3q+vt/xtzdlAei8QegQInqeCrZ0A4GtoCZHxZmAfA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}