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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '9005b01c8762ecc36d27aa833ed88daf310ec2f2af381860c9fef175eaa53734' 
  AND token = 'ak5i8XPIaV1QpNbfpgtbRInyj4eZm8dvvVrw7Ryx16g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}