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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '1499cdf79bd3b257d5e0e40ae27ae870da899da193d5f146ed53269d8010076e' 
  AND token = 'FZVLMFhtamxEupT61uVYWF4LQYZ0d3FsKQRMNyymCc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}