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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '3a497341089ebdc30114b0a251e88c2e25878224834e01acd72ff03318a0b785' 
  AND token = 'U11r850Z/kWyhsLRQNRRuL3DhU3wXWGx8/mZIYlflF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}