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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '49c1d7b3bc5265af8cf2c6b81ab566f897a97c187542dd8b16aae475322d0489' 
  AND token = 's6Q0dsI4OQOOxsr9k6EHA3Axu9eyKiHptofOAThh2Yo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}