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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '78819d9b9eb606b6935ceb26ad7b8e28d5d930323b5bd74d9be297cca854e11a' 
  AND token = 'AuBqHSf1ehSS3RJtdFT3yzhyInvrjuWQ0pCSQnzHpSo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}