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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'c35051ab8ba336852d99587b87dd30ee5e8033aded4dc288ab379c9f0808670d' 
  AND token = '8U/S/uVW9fIXBBMQ6p/L2VyndL+BEw4fNDnoCrLQjvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}