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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '250ef936cfd8fc26dc74869e9283bcb3470aa8bef1a99fea089e1e18eeaf63c7' 
  AND token = 'rMGr4KZUIyRpRTvcl0ExnnTFGbzb3BlIQvxvEzAfnCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}