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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'a156ad3adae1e8129e01e7bd60218bd7f0e069beb5ab66a250aebdab40808111' 
  AND token = 'dl3MEgY+8hMg4fWLtOUEz8HqONkXnPZNNn2zqfoe2qc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}