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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'e81219a426e642c3cac33abd512da46b61e504a74c04fb07f35cb2661167a9cd' 
  AND token = 'bLvPubX7KDStxlrdtim8TFiZIt4yZH/TOwbLUBpqw8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}