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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'f2f19795f6ab01422cfa06647c0abec48634f84dcd0b81e8ef6f06feda02a374' 
  AND token = '2pPUcU6DLy0KzGQGumSYfQsm7IIMYuevIofa2pRxUNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}