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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '5746e31c84c21e35460e12cbe261d0e0ae2cdca855317f1cb5ac80b5b9e11868' 
  AND token = '8NxLeu/twRuYWKBmAtJeZx5HOY6jC4bWjy6j4TP25B0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}