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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '4f37036e9fb34698c6ddc8f82cbe2f72b239adb7e129e803c813f877821522c6' 
  AND token = 'zntmCUFpXuLvsGTYS4v5V9f3MbcxKpdbpphustBouy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}