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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'a667afe1bbbccf98af6696f3ac22ad0365c9d6691a81348ef8c6fcbf2a492daf' 
  AND token = 'EDmXV8uOc2j6tWjBWmUIXmedu2CakzOum/W1nKJonM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}