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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'e724f05852eb4be2c1f27f50f7a327fe0b00bb906b15e9c345f8e59cc3c29b04' 
  AND token = 'ypjsPH7j4IJWUHlUDKtDmPB0VsXzkQ4vRd7JtKA6c6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}