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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'c57e0c30537661d61d08f893bd669fc7d1508d1e0a890cea155131665d2fb2f1' 
  AND token = 'DLXe8aXqmi8Zsgxdg2TdBnS0wJwlMD7ATyavo3SMy5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}