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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '54211b2a3ff5c9800543aa5d1508a0983c3f5a983146b21088b6c3a1dba65f4d' 
  AND token = 'NdmSLTbTns9GmaBDsQTT6LtW/eJ56NrSSH5b87HOXqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}