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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'b80da3fe0e871c330d03341924a6fa503e121d6d2823b1062c5836fca0620f4d' 
  AND token = '0uKxlS0xfs61bAMpWOu2A/VQdp8B/zHe+ruoaR89U3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}