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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '1241fd124500064e4047471f5fd75f26dde026a17e16fc21c5de4cde69000cc8' 
  AND token = 'H/XTH3DThMq3vI2IbCieMlsjXlXENuBmox654pvLZcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}