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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '1452cfc160c669374acb3334adafb37f335d8bc5efd52b18008d4e68b2217777' 
  AND token = '4yFswUEMhxTWIQEyMxR4GAixUb25gP7/mhlvo/4PSrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}