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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '24e4266d7df422c8214e6b2161dfb982b486269ec3b6c880498222c3252f94d3' 
  AND token = 'sd9AjOOnxK6InOmFmsWlZQ2ldaUOwOZ6wm6rHlRek7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}