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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '35bb69a5735000f622854d0e4202767af255b35a9366f50a5e692d0af01db8b3' 
  AND token = 'PeJVnbZJso+VToKMboyVWU63iyZehWReQgvY0kz38e0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}