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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '661bf25dff8628aa572b255f7d42bb7f2a5c32274fc3c445d439455142ed5e2e' 
  AND token = 'PcK1Hws1nz6qXzaT8lQprA7Z7O4PnF4upopkEZ2jOAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}