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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '0bdfb2588a4b5188bd49968e67fb1f13b98d3504c84602639343778d0d5bd76d' 
  AND token = '+14LXHV168vDRdLG9GQi1NrPsgx146NNrymrzQnP78o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}