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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '48e65adcd11dbe289fd8813bd307e981812e30ddffcf900680e432dfcb1cc071' 
  AND token = '6lM9Zp0xMEmKv+kly83+8rFKO7usyfG+ozKauX5RcR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}