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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'b4c144a9dcc18a308de0e1cee88379421b2417b1410e034c90451996339bd545' 
  AND token = 'RA6P4glmekcBZUZdg0bUrtbVS2cswi7O2+Q0F2HyUVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}