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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '9ca44bc262773d568f951e82e17dcc2d75da09dbb37bf5282cecee1fbff146ef' 
  AND token = 'U0Xsivdt/R2Awsur1PQXkz5H+Hu7vT9hkeZIYi6HfTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}