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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'bded0c294e8c497a5642dc2bb826674221a2e0d47b6172aad718564ac681b7e7' 
  AND token = 'trR8hEi1tWlefWBQLExcuWq+w6g2l6Z1w4d8+y+o/zk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}