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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'd27c80d15cd426003b184ac986a9d3323e5ce6d5f4f4b3209c38ffab7918508a' 
  AND token = 'JjrZ5Nl9TDe4Ypg514jLUeW9diETOaHSWOtSrxWAuPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}