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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '44148c6b9bd247d488a9bc3e365c1d07d7f86b2dc20bc9b819691c03074d0281' 
  AND token = 'DUUf61FwepcbH4XSQyrH9APFotCsfbq0kax+47+mp5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}