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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '27262d53f573ae5c9be3f2e71d9bce9ff40c793e2f0ff75f2c9ae156612eaa00' 
  AND token = 'OHnJgBwhIHs672ZwAvdUroxiY6X2DyCfwDFGb4mDjps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}