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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '603a6a21d843fdbebd7bd88632f654855dfdc155383b175daacb4d91e41379ba' 
  AND token = 'BU4rYjA8cCSdenNcutx4veG9bvyGzIbk5FZi0sQ515o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}