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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '480494c9d2aabcd7aab0b2356b1b09bed471f689cca6e0d06737d34749bc259c' 
  AND token = 'JeG5Pzz3WoHmRyVh6fuD9Mm34vhXr4PTDDKNPdaHOPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}