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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '281f212abedc58a0b16a0a20a253906ff0824d751f95dd8d7a5e1b690f0f9ffe' 
  AND token = 'uZxyo09WXUHL6EQ1aD5DrE5jYB6Ca9+KLpT7hayMfHo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}