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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'c9b21823e501b5f5164b8bd9f82414ae5a3ce42194e29decd59b32abad937f2f' 
  AND token = 'OOrdAluduOLkNf/BKR/hBi/iDmp+MyHqKwk7QDs4MHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}