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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '0fcd61adae45991abfa39cdd681106c6e795f756b67572dfc0180ef6d5d99510' 
  AND token = 'p53CUOZswLWZ008/YAXQtoADwU1ZyfPWgNmItv8jNWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}