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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'c50c9b6147d4079d0221941a311888f9c519a2c54736e56171f5fde7cd5761a1' 
  AND token = 'IbwXdAbzkfzg+q5RsDo/BCM4NSE1shBR8cde4JSILuo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}