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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'd3ae255ff9387ea8ca109ce436db80f20f335914e0e431cc2801b4a696a79eff' 
  AND token = 'P+snA+y4s4BxUY1zwePKI2uwjA0jBkqAWgadnTFTzbE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}