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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '2f442a083c972e42ab72977862013e254369ff87316d9a03e2395c7e68762944' 
  AND token = '+4bH7Nmi5Av3LejEn19PrlTwixr0Z1PD1c5cjVxKmoc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}