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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '2ee0233f1edab04db256ba754b6f18ea2845e5b3674a837a57537750dc0db732' 
  AND token = 'emeXiv+gk6GirlS5aieZZJvoyskW3kJholraBl+kvPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}